Targeted Projects
Industry partners will collaborate in PrecisionALS through unilateral targeted projects. These projects address specific topics of interest to the individual partners and cross-reference to the research programme work packages. Examples of our current targeted projects are described below.
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Retrospective study of the natural history and genetic subtypes of ALS patients
This project involved an analysis of the natural history and genetic subtypes of ALS patients using data extracted from Precision ALS partner sites.
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Prospective Pan-European Study of ALS Using an Integrated Patient Data Platform (PRECISION-ALS)
This project involves the prospective collection of detailed and harmonised data from people with ALS for inclusion and analysis on a single searchable.
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Biomarker Discovery including proteomic analysis of Biological Material
The purpose of this study is to examine what new insights we can get into ALS by analysing samples collected over time in conjunction with their detailed clinical data.
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Discriminatory power of home-based functional neurophysiology to characterize cognitive decline in participants with ALS/FTD
The purpose of this project was to evaluate the utility of a home based EEG testing kit against standard in-person neuropsychological testing as a potential for another way of tracking the cognitive status of people living with ALS over time.
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Customisation of the Precision ALS Platform for the purposes of Multiple Sclerosis
This project involves developing the Precision ALS Platform further to customise it for use with another neurodegenerative condition, Multiple Sclerosis (MS).
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Disease Progression and Survival in Amyotrophic Lateral Sclerosis (ALS): A Real World European Cohort Study.
This study aims to generate new scientific insights in the causes, progression and treatment of ALS by analysing a large dataset creating by combining data from all Precision ALS partners sites.