Targeted Project 3
This Targeted Project titled “Analysis of Volumetric MRI and DTI in amyotrophic lateral sclerosis (ALS) patients”, involves Irish and Dutch data sets and will focus on statistical models which will be implemented for cross-sectional and longitudinal analyses. Some complex models will be implemented based on raw data output of the primary imaging suites as well.
Understanding ALS clinical and biological progression over time is needed to advance innovative clinical trial tools to enable improved confidence in ALS drug development. There is also clear potential to reduce costs and increase productivity in clinical trials through developing and implementing robust biomarkers and clinical tools.